1. Heel abscess and pregangrenous changes with Diabetes Mellitus       55 year old diabetic had a small wound on the heel which he neglected. It became worse and an abscess developed on the left heel pad. Pregangrenous changes started on the dorsum of the left foot.     He was treated with the standard treatment protocol for non-healing wounds plus Ozone. External Ozone Oxygen Gas Mixture was given by bagging the affected limb in a plastic bag. First 10 sittings were given daily and last 5 sittings were on alternate days. He showed good response and the granulation tissue was very healthy. Skin grafting was done with 80-85% graft acceptance.           2. Chronic Eczema       71 years old man had rough, thick, dry scaly skin on the anterior aspects of both the ankle joints, since last 10 years. It started on the right side and followed by the left side within 3 years. He developed generalized itching since 3 months. A well defined, very dry, rough, dirty yellow colored lesion with horizontal fissures at the skin fold was present on the anterior aspect of the right ankle     Left ankle had similar lesion but half in size and less severe. Diagnosis of chronic eczema was made. Ozone therapy was given in 3 ways – External Ozone application with bagging, local application of Ozonated Oil and rectal insufflations for faster relief and generalized itch. After 15 sittings, his itch was gone, his lesion has improved significantly and he was feeling well and energetic!           3. Bed Sore       38 years old male was admitted with high fever for the past 3 weeks. In spite of treatment, his fever was not coming down. He was a long standing paraplegic. He also had a bed sore on his right buttock, almost bone deep, for the past 3 years. In spite of regular dressings, there was no improvement in its condition. It was covered with copious foul smelling discharge. The lips of the ulcer were thickened. Ozonated Oil was used on experimental basis. Ozonated Oil was applied twice daily after cleaning the wound. A dramatic improvement was noticed.     The discharge was reduced and the ulcer started showing healthy granulation tissue. Surgical debridement was done and the entire ulcer was closed in layers. Daily dressings were carried out with Ozonated Oil. The healing was satisfactory. The surrounding skin improved in its texture, it became smooth and supple. Thus the entire ulcer healed by a primary closure. The patient was discharge in a satisfactory condition. An ulcer, which one would expect to take at least 10 weeks, healed within 3 week.           4. Cerebellar Stroke       A 70 years old male, known diabetic, hypertensive & post coronary artery by pass surgery status, presented with history of weakness of right side of body & postural imbalance. He had a history of sudden onset of vomiting & weakness before 15 days & was admitted to hospital at Mumbai. MRI of brain with angiography was done & was diagnosed to have cerebrovascular stroke. MRI Showed Acute infarct in right posterior inferior cerebellar artery & old ischemic lesion in left basal ganglia, corona radiata & bilateral parietal white matter. After 1 week of stay he was discharged. At the time of discharge, he had postural imbalance, Weakness of right side of body and positive Romberg sign. On examination, Romberg sign positive, Intentional tremor with dysmetria & dyssynergia, Decreased muscle tone, Dysdiadochokinesis and ataxic gait were present. He was started on Ozone Therapy & Physiotherapy. Ozone therapy included Major autohemotherapy twice a week, rectal insufflations on alternate days. Physiotherapy included all coordination exercises, balance exercises, & Gait training. After 10 days of treatment (From 27/4/07 to 6/5/07), His Intentional tremor was reduced by 60%; all co-coordinative movements were improved by 40%. Romberg sign became negative. He was able to get up from chair with ease. He could perform all his day to day activities without support & he was feeling very fresh. Postural imbalance was reduced. He was walking without support & no swaying.           5. Ca vaginal wall       Mrs. K S, age 47 Muslim lady was a case of post op Ca vaginal wall. She had Ca cervix in 2004 which was operated in KEM hospital. She had taken 6 chemotherapy following surgery. She complained of severe pain & discomfort in lower abdomen, profuse leucorrea, dribbling of urine and involuntary urination. She was very depressed and irritated. She was given ozone therapy by Rectal insufflation and Vaginal insufflation, twice a week for a total of 20 procedures each. Patient improved within first 4 sessions. Her vaginal discharge completely disappeared! She started passing proper stools and gaining control over her micturation. Her appetite improved. Above all, she improved psychologically. She became better, happy & cheerful. Her zeal for life returned.           6. Osteo arthritis knee joints       Ms. J 54 yrs old housewife was suffering from pain in both the knee joints since 2 years. She was advised knee joint replacement. Knee joint lavage was given 3 yrs ago. She had reached menopause 12 yrs ago. This was the case of osteoarthritis. Ozone therapy was started in the form of subcutaneous peri articular knee joint injections, injecting 5 ml of Ozone around one knee joint. She was given injections twice a week, and continued for 4 weeks. At the end of 4 weks, her pain was reduced by 80%.           7. Intestinal tuberculosis and erosive gastritis       21 yrs old typist came with recurrent burning pain in stomach and vomiting off and on since 7 yrs and was not relieved with the existing treatment. He also suffered from diarrhea. He had suffered from Abdominal Tuberculosis at the age of 8yrs. He was treated for TB for 6 months then. Presently, he could not eat heavy meals as his stomach would not retain it. It would give rise to burning and vomiting. Endoscopes revealed Erosive Gastritis in Nov 2004. He was given rectal Ozone twice a week for 5 weeks. He started showing good results after 3 visits only and after the treatment was over he was very happy as his bouts of Diarrhea stopped and finally he got rid of the everlasting (as termed by him initially) burning pain in stomach!           8. Prolapsed intervertebral disc       Mr. K P, 42 years old athlete presently working for BMC had a prolapsed intervertebral disc between L4 and L5 since 6 months, after a football match. He had to bend a lot due to the nature of his supervisory work. It gave him lot of pain. He was given paraspinal Ozone injections, (An OPD procedure) twice a week for 5 weeks. His pain was reduced by 75% only after 4th injection. On completion of the course, he was totally pain free and working.           9. Varicose veins and chronic fatigue syndrome       PS, 36 years old housewife was suffering from pain near the calves especially after standing for 1-2 hours. She had developed varicose veins post delivery since 3 years. Her perforators near the calf were incompetent, leading to purplish discoloration near the calf. She would get so tired that she had to have rest in the afternoon before she could face her evening chores. She was started on rectal Ozone twice a week for 10 procedures and then Major Autohemotherapy was added alternately. She finished 15 Rectal Insufflation and 5 Major Autohemotherapy. Her pain was reduced by 80%. Her chronic fatigue is totally gone! She felt very energetic and could walk on a trade mill for 30 minutes! Her discoloration had also lightened considerably.           10. Sinusitis and asthma       23 years old school teacher was suffering from allergic rhinitis and sinusitis. Running nose was her constant companion. It was due to chalk dust allergy. She had difficulty in breathing especially at night, while sleeping; because of nose block which would finally result into headache - predominantly in sinus regions. She had this problem since 2 years. Past history revealed Bronchial Asthma from the age of 12 years. She was taking tablet Asthalin and Rotahaler in emergency. X-ray PNS showed that Para-frontal sinuses were filled with fluid. She was advised ear insufflation twice a week. She continued the treatment for 5 weeks. She had very good result in Sinusitis as well as in asthma. Her nasal symptoms disappeared. Her headache was gone. Her X-ray showed clearing of PNS. Her asthma was also much better controlled.